Description

What is Anti-Histamine Soothing Active?

Anti-Histamine Soothing Active (product code YLBMS) is a ready-to-use liquid soothing system built around Hydroxyphenyl Propamidobenzoic Acid, a synthetic analogue of the calming avenanthramides found in oats (also known as dihydroavenanthramide D), solubilized in a skin-friendly vehicle of Butylene Glycol and Pentylene Glycol. Its molecular structure closely resembles tranilast, a well-known anti-allergy and mast-cell-stabilizing agent, enabling it to calm itch, cool redness and reduce the appearance of edema in reactive, sensitive or irritated skin. Supplied as a pale yellow clear liquid, it is effective at 0.2–3% and stable from pH 3 to 8. Reported data show up to 97% redness reduction at 50 ppm, 78% edema control at 30 ppm, relief of itching, edema and erythema within around 30 minutes, and ≥99% on-skin control over 120 minutes.

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Key Benefits

• Fast anti-histamine soothing: helps calm itching, stinging and the sensation of irritation within minutes.
• 97% redness reduction: recorded at 50 ppm in a human anti-histamine test on the inner arm.
• 78% edema control: measured at 30 ppm in a dermatitis model; tranilast-like structure.
• Long-lasting comfort: ≥99% on-skin control maintained over 120 minutes.
• Oat-derived science: a synthetic avenanthramide analogue with antioxidant, anti-irritant benefits.
• Wide formulation window: stable at pH 3–8 and easy to incorporate into leave-on products.
• Ready-to-use liquid: pre-solubilized in butylene and pentylene glycol for simple, reliable processing.
• Versatile applications: sensitive care, redness relief, anti-itch, bite and after-sun products.

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FAQ

Q1: What is hydroxyphenyl propamidobenzoic acid? A1: It is a synthetic analogue of oat avenanthramides (dihydroavenanthramide D) with anti-irritant, antioxidant and anti-histamine-like soothing properties.

Q2: How quickly does it work? A2: In the reported tests, itching, edema and erythema were relieved within about 30 minutes at 30 ppm, with control lasting over 120 minutes.

Q3: Which products is it used in? A3: Sensitive-skin serums and creams, redness-relief and anti-itch products, after-shave, after-sun, post-procedure, baby and bite-relief care.

Q4: Is it easy to formulate? A4: Yes — it is a clear, ready-to-use liquid, added at 0.2–3% and stable across pH 3–8; validate compatibility in your own system.